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* Corresponding authors

a State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China E-mail: [email protected]

b Center for Biological Science and Technology, Beijing Normal University, Zhuhai, Guangdong Province, China

c C-MER Dennis Lam and Partners Eye Center, Hong Kong International Eye Care Group, Hong Kong, China

d Haikou Orthopedics and Diabetes Hospital, Haikou, Hainan, China

e National Engineering Research Center for Marine Aquaculture, Institute of Innovation & Application, Zhejiang Ocean University, Zhoushan, Zhejiang Province, China E-mail: [email protected]